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Download Chinese Drugs of Plant Origin: Chemistry, Pharmacology, and by Professor Dr. Weici Tang, Professor Dr. Gerhard Eisenbrand PDF

By Professor Dr. Weici Tang, Professor Dr. Gerhard Eisenbrand (auth.)

Traditional chinese language drugs has been used for hundreds of thousands of years by means of a wide inhabitants. it truly is presently nonetheless serving some of the overall healthiness wishes of the chinese language humans; and nonetheless having fun with their confi­ dence it really is practised in China in parallel with glossy Western scientific remedy. as well as clinical companies dedi­ cated to fashionable Western drugs, e. g. the chinese language Academy of clinical Sciences and diverse scientific colleges, a chain of parallel associations were proven in China to advertise conventional chinese language medication, similar to the Academy of conventional chinese language medication and coaching associations. just about all hospitals in China have a division of conventional drugs. additionally, lots of medical journals are devoted to conventional chinese language medication, overlaying either experimental and medical investigations. Medicinal fabrics represent a key subject within the remedy of affliction in accordance with conventional chinese language medication. The chinese language Pharmacopoeia (1985 variation) is for this reason divided into sepa­ fee volumes, quantity I containing conventional chinese language medicinal fabrics and arrangements and quantity II containing pharmaceu­ tics of Western medication. The oldest chinese language overview of medicinal fabrics, Shennong Bencao Jing (100-200 A. D. ), coated 365 natural medications. The clas­ sic compilation during this box, Bencao Gangmu (Compendium of Materia Medica), was once released in 1578 by way of Li Shi-zhen and recorded as many as 1898 crude medications of plant, animal and min­ eral origin.

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Additional info for Chinese Drugs of Plant Origin: Chemistry, Pharmacology, and Use in Traditional and Modern Medicine

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In mice, Lv. LDso values were 1600-3400 mg/kg. By contrast, the toxicity of those species containing diester bases, with an acetoxy residue at C-8 and benzoyloxy or anisoyloxy residues at C-14, is very high. The Aconitum species that contain mainly an aminoalcohol of C 19 diterpene alkaloids display intermediate toxicity with LDso values of 210-260 mg/kg [86]. Aconitine exhibits a noncompetitive, inhibitory effect on pig heart aconitase in vitro. This suggests a possible molecular basis for the toxic and pharmacologic actions produced in experimental animals by aconitine [87].

Okuda T, Yoshida T, Kuwahara M, Memon MU, Shingu T (1982) Agrimoniin and potentillin, an ellagitannin dimer and monomer having an (X-glucose core. J Chern Soc Chern Commun 163-164 4. Su GS, Su SW, Zhu TR (1984) Studies on bacteriostatic components from Agrimonia pi/osa Ledeb. J Shenyang Coll Pharm 1:44-50 5. Li LC, Cheng YP, Yu PL, Li Y, Kai YC, Wang TS, Chen IS (1978) Studies on the active principles of Shianhotsao. III. Syntheses of agrimol A, B, D and E. Acta Chim Sin 36:43-48 50 Agrimonia pilosa Ledeb.

Vilmorrianine B was shown to be identical with yunaconitine, vilmorrianine C with foresaconitine. The structure of vilmorrianine A was determined [24]; isolation of the fourth alkaloid, vilmorrianine D (3-40), was also reported [25]. Vilmorrianine D is identical to sachaconitine. 7 Aconitum koreanum Guan-fu bases A-G are alkaloids isolated from A. koreanum [26, 27]. The structure of guan-fu base G (3-41) was determined on the basis of spectral analyses and X-ray analysis of the methyl iodide to be a C 20 diterpene alkaloid of the hetisan type.

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