By Radovan Zak (auth.), Robert M. Dowben, Jerry W. Shay (eds.)
Motility is a primary estate of dwelling platforms, from the cytoplasmic streaming of unicellular organisms to the main hugely differentiated and devel oped contractile procedure of upper organisms, striated muscle. learn on var ious elements of motile platforms in muscle and undifferentiated or non muscle cells has been constructing at an ever extra speedy velocity within the laboratories of investiga tors with a large choice of backgrounds utilizing methodologies various from me chanics to the main refined actual measurements. major contri butions to our figuring out of motility are coming from the disciplines of phone biology, biochemistry, pharmacology, molecular biology, biophysics, and body structure. The findings have relevance not just to easy scientists yet to clinicians in such various fields as cardiology and neurology and to scientists within the extra conventional actual sciences. telephone and Muscle Motility is a brand new multivolume sequence of essays through exotic examine staff in quite a few fields whose paintings has a typical thread of facing one element or one other of motility. The essays are supposed to specialise in issues of present curiosity, to be serious instead of exhaustive, and to point the present traits of study efforts. The sequence is meant to foster an interchange of innovations between a number of staff within the box and to function a reference for college students and employees who desire to familiarize themselves with the most up-tp-date development in motility.
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Additional info for Cell and Muscle Motility
1978). In contrast, the hyperthyroid state in the rabbit is associated with increased shortening velocity and with an increase in the ATPase activity of ventricular myosin. No change in the content of light chains has been found (see Morkin, 1979); rather, the change seems to reside in the heavy chains. , 1979). , 1980). , 1979). 5. 1. Control of DNA Replication Very little is known about the mechanisms that control DNA replication in muscles, or in other organs of higher animals. , 1974) and thymidine kinase (Claycomb, 1975).
The distribution of myosin isozymes in adult hearts appears to change in accordance with the hemodynamic load. Surgically produced aortic constriction or insufficiency results in decreased ATPase activity of ventricular mysoin. At the same time, there is increase in the relative content of isozymes VM-2 and VM-3, which have lower ATPase activities than VM-l. , 1979). No change in the relative content of light chains in the heart has been found under conditions that result in a decrease of ATPase activity.
29: 113. , 1972, Appearance of acetylcholine receptors during differentiation of a myogenic cell line, Prac. Natl. A cad. Sci. A. 69:2762. , 1976, Myosin light chains of developing fast and slow rabbit skeletal muscle, FEBS LETT. 67:68. Perry, S. ' II (A. T. ), pp. 319-328, Excerpta Medica, Amsterdam. Perry, S. , and Grand, j. , 1979, Mechanisms of contraction, Br. Med. Bull. 35:219. , 1977a, Coexistence of fast and slow type myosin light chains in single muscle fibers during transformation as induced by long term stimulation, FEBS LETT.