By Klaus J. Zülch M.D., Dr. h.c. (auth.)
The 3rd American version has been thoroughly revised and improved, even supposing components of the textual content of the second one variation were integrated. I desire to recognize once more the superb translation of the previous variants by way of Dr. ALAN B. ROTHBALLER and the past due Dr. JERZY OLSZEWSKI. With this variation i've got the overall topic of the unique German variation released in 1951. notwithstanding, i've got attempted to contemplate smooth thoughts and the various new guides with reference to mind tumors. in the meantime, an early wish of mine has been fulfilled through the final touch and book of a type which might be understood world wide and expectantly be used greatly, specifically, the classi fication of the area overall healthiness association: Histological Typing of Tu mours of the imperative anxious method (1979). The class which I utilized in the 1951 version is particularly just about the ultimate development of that authorized by way of the area overall healthiness association (WHO), for the reason that either stick with the road of the BAILEY and CUSHING classifica tion of 1926/1930. To consolidate our previous strategies and studies we now have reclassi fied our number of 9000 situations with the help of my co-workers Dr. M. FUKUI, Dr. A. SATO. Dr. E. SCHARRER, Dr. E. SIMON, and Dr. J. SZYMAS. within the final decade huge atlases were released, one known as an Atlas of the Histology of mind Tumors 1 (in six languages) and a moment one known as an Atlas of the Gross Neurosurgical Pathology 2.
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Additional resources for Brain Tumors: Their Biology and Pathology
Rathke's cleft cysts are intrasellar epithelial cysts. 3. Epidermoid cysts are lined with a keratin producing squamous epithelium. Their contents are typically brittle, white and pearly. Malignant transformation is very rarely seen. 4. Dermoid cysts are lined with keratin-producing squamous epithelium. Their contents are more smeary and cheesy than brittle; they contain skin appendages, and hair and rarely teeth may be included. 5. Colloid cysts of the third ventricle occur in the foramen of Monro and their origin has not yet been clarified.
Further pieces of evidence came from histochemistry as demonstrated, for example, by BINGAS (1966, 1970), who showed a decrease of alkaline and an increase of acid phosphatase in progressive anaplasia, although the dihydrogenase increased. Histochemically, he found the separation of glioblastoma on one hand and astrocytoma and oligodendroglioma on the other possible when based on these criteria. Later efforts were reported, for instance, by ODA (1974), who tried to find tumor specific antigens.
2. Rare forms of anaplastic ependymomas may resemble glioblastoma or medulloblastoma, although features of ependymal differentiation can still be recognized (grade III). 3. Choroid plexus papillomas are composed of a papillary pattern of low columnar or cuboidal cells covering a delicate core of vascular connective tissue (grade I). Some of these tumors are heavily calcified (usually in the temporal horn). 4. There may be - although rarely - anaplastic forms of this tumor (grade III) with a blurred achitecture, pleomorphism, and mitoses.