
By J. Park
This re-creation has been accelerated and up to date to incorporate extra glossy issues, and contains new examples, illustrations, difficulties, and case reviews.
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Additional resources for Biomaterials:An Introduction
Example text
These digital systems most often utilize two immiscible phases with the continuous phase being a hydrophobic fluid, such as mineral oil or air, and the disperse phase being an aqueous solution, as is characteristic of biological samples. Droplets help suppress unwanted Taylor dispersion and evaporative effects, and have been used for many applications, including sample transport, mixing, and particle synthesis [24]. Electrowetting is a technique in which electric potentials are used to alter the local surface wettability of a substrate at opposing ends of a droplet, thereby inducing a pressure gradient within the liquid and subsequent droplet motion.
Unger MA, Chou H, Thorsen T, Scherer A, Quake SR (2000) Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography. Science 288:113-116. 27. Gu W, Zhu X, Futai N, Cho BS, Takayama S (2004) Computerized microfluidic cell culture using elastomeric channels and Braille displays. Proceedings of the National Academy of Sciences 101:15861-15866. 28. Namasivayam V, Larson RG, Burke DT, Burns MA (2003) Transpirationbased micropump for delivering continuous ultra-low flow rates. J Micromech Microengineering 13:261-271.
Nat Meth 4:665-670. 81. Ladiges W, Kemp C, Packenham J and Velazquez J (2004) Human gene variation: from SNPs to phenotypes. Mutation Research 545: 131-139 82. S. Census Bureau" (2008) accessed 2008. online. gov. Chapter 2 Materials and Microfabrication Processes for Microfluidic Devices Arash Noori, Sarvesh Upadhyaya, and P. Ravi Selvanganapathy McMaster University, Hamilton ON L8S 4L7, CANADA Correspondence should be addressed to: P. ca) Keywords: Microfluidics, microfabrication, Silicon, Glass, Parylene, PDMS, Hydrogel, Paraffin, Polyimide, bulk micromachining, surface micromachining, micro injection molding, hot embossing, micro stereolithography Abstract This chapter elaborates on the varied materials and microfabrication techniques used in the manufacture of microfluidic devices.