By Allen I. Laskin (auth.), Alexander Hollaender, Allen I. Laskin, Palmer Rogers, Stanley Dagley, Richard Hanson, Lawrence McKay, Joachim Messing, Claire M. Wilson (eds.)
Allen I. Laskin Biosciences study Exxon examine and Engineering corporation Linden, New Jersey i used to be contacted within the Fall of 1981 via Professors Martin Dworkin and Palmer Rogers, of the collage of Minnesota and requested to take part within the orgnization of the 1983 convention within the sequence, "Interface among Biology and Medicine". They and the opposite participants of the advisory committee had the imaginative and prescient to achieve that this used to be a time to leave slightly from the conventional topic, in view that one of many significant parts of curiosity within the organic and comparable sciences nowadays is that of biotechnology in a broader feel than its impression on drugs by myself. In designing the layout of the convention, we thought of one other issue. there was a plethora of meetings, symposia, and conferences on biotechnology during the last few years, and the faces and subject matters became fairly everyday. there was a robust emphasis at the improvement of the know-how and the "biotechnology industry"; much less cognizance has been paid to the technology in the back of it. One may well get the influence from a few of these conferences and from the preferred press that biotechnology has only in the near past sprung up, it sounds as if complete blown; the very primary medical discoveries and the nice physique of one ALLEN I. LASKIN 2 carrying on with study that varieties that foundation for the know-how is frequently obscured.
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Tavernier, G. Haegeman, and W. Fiers. 1981. Nucleotide sequence of the chromosomal gene for human Fibroblast (B 1) interferon and of the flanking regions. Gene 14:137-143. 10. , J. van Damme, H. Claeys, H. W. Heine, A. Billiau, C. Vermylen, and P. de Somer. 1980. Interferon induced in human leukocytes by mitogens: production, partial purification and characterization. 11. Eur. J. Immunol. 10:877-883. , J. Content, E. DeClereq, G. Volckaert, J. Tavernier, R. Devos, and W. Fiers. 1980. Isolation and structure of a human fibroblast interferon gene.
IodH (\/ ~ ~ = ~ '" eD ..... , ... '" (\/ I •• • • 0 Fig. 5. The 32P-labelled Alu family The 32P-labelled Lane 1, HindIII + Sac I digest of pB9KB-l; 2, The IFN-y gene region is shown as a smaller box with solid bars for exons and open bars for introns. (cross-hatched) of the Alu family repeat is presented above. Mapping of the six different hybridizing signals ~ :z: EcoRI digest of human genomic DNA. J trJ ~ 1-3 trJ :z: H trJ :z: ~ H ~ ::II 8, EcoRI digest of AG6; 9, BamHI digest of AG8; 10, EcoRI + BamHI digest of AG8; 11, of AG5; 5, XbaI + HindIII digest of AG5; 6, XbaI digest of AG5; 7, XbaI digest of AG9; HindIII + HpaI digest of pB9KB-l; 3, BamHI + HpaI digest of pB9KB-l; 4, EcoRI digest results are presented to the right.
This PANACEA protein sequence was then used as the starting point for the analyses described in the text. The PANACEA amino acid sequence has been entered into the computer. Using the computer's ability to reverse translate, we will project all possible coding sequences for this protein. We will COMPUTER APPLICATIONS 25 Enter the low amino acid location. lensth of seSRlent: 33. 51111 23 Chains 1. ~! ~ 32 PHE ASN GLU MET PRO MET ASP TRP PRO PRO ILE SER 94 TTC AAC GAA ATG CCA ATG GAC TGG CCA CCA ATA AGe TTl' AAT GAG Fig.